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KMID : 1039620210110050365
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Korean Journal of Family Practice
2021 Volume.11 No. 5 p.365 ~ p.371
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Epidemiological and Clinical Characteristics of Hospitalized Patients with Community Acquired Coronavirus Disease 2019 Infection According to Severity Classification
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Jang Dong-Sung
Yun Han-Sol
Lee Seock-Hwan
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Abstract
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Background: In December 2019, coronavirus disease 2019 (COVID-19) emerged in Wuhan, China and, thereafter, rapidly spread worldwide, includingSouth Korea. The spread of COVID-19 is still ongoing throughout the country, but information on the clinical characteristics of affected patients inthe community outbreak is limited.
Methods: We obtained epidemiological, demographic, clinical, laboratory, radiological, and treatment findings of hospitalized patients confirmed byusing real-time reverse transcriptase-polymerase chain reaction (RT-PCR) tests. Clinical outcomes were analyzed according to National Institute ofHealth (NIH) clinical spectrum.
Results: The mean age of the 214 hospitalized patients infected with COVID-19 was 47.0±17.7 years, and 72.9% of the patients were female. Accordingto NIH clinical spectrum, 104 (48.6%) of the patients were/had ‘asymptomatic/mild illness’, 63 (29.4%) had ‘moderate illness’, 47 (22.0%) were/had‘severe/critical illness.’ Common symptoms included cough (67.8%), fever (63.6%), and sputum (54.2%), and a significant proportion of the patientspresented gastrointestinal symptoms such as nausea/vomiting (45.8%) and diarrhea (45.8%). Almost half the number of patients (109; 50.9%)developed pneumonia during the clinical course, and lymphocytopenia was present in 108 (50.5%) of the patients on admission. The mean lengthof stay in hospital was 27.4±16.2 days; 140 (65.4%) of the patients were discharged, 61 (28.5%) shifted to the residential treatment center, 11 (5.1%)transferred to the tertiary hospital, and 2 (0.9%) died.
Conclusion: In this single-center, retrospective, descriptive study, fever was the most common symptom and a good predictor of disease progression.
Old age and chronic underlying diseases, such as hypertension and diabetes mellitus, may be risk factors for worse condition.
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KEYWORD
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COVID-19, Epidemiologic Studies, Clinical Characteristics, National Institute of Health Clinical Spectrum
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